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Article ID: 555944

Race Shown to Affect Severity of Lupus Disease

Health Behavior News Service

In patients with systemic lupus erythematosus, their race can affect how severe the disease will become, according to a new study.

Released:
8-Sep-2009 12:00 PM EDT
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Article ID: 554991

New Online Forum for Autoimmune Disease Patients Provides Virtual Support Groups

American Autoimmune Related Diseases Association (AARDA)

Patients suffering with chronic autoimmune diseases from every corner of the globe can now find one another online to provide support, share experiences, and form relationships. The new Autoimmunity Forum launched by the American Autoimmune Related Diseases Association (AARDA) is a virtual support group community nearly 400 members strong.

Released:
6-Aug-2009 2:00 PM EDT
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  • Embargo expired:
    27-May-2009 7:00 PM EDT

Article ID: 552790

Team Develops DNA Compounds That Could Help Treat Lupus

University of Iowa

A research team has generated DNA-like compounds that effectively inhibit the cells responsible for the most common and serious form of lupus. The findings could eventually lead to new treatments for this difficult disease, which affects up to one million Americans.

Released:
27-May-2009 2:00 PM EDT
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  • Embargo expired:
    15-Apr-2009 5:00 PM EDT

Article ID: 551048

Alternative Therapy for Lupus Nephritis

American Society of Nephrology (ASN)

Lupus is a rare but serious disease that mainly affects women of child-bearing age and occurs when the body's immune system goes awry, damaging a variety of organs. When kidneys are targeted, patients develop lupus nephritis, which can result in kidney failure and death. Lupus nephritis is often treated with the cancer drug cyclophosphamide, which suppresses the immune system but also causes hair loss, nausea, vomiting, and infertility.

Released:
10-Apr-2009 11:15 AM EDT
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Article ID: 550522

Gene Linked to Lupus Might Explain Gender Difference in Disease Risk

UT Southwestern Medical Center

In an international human genetic study, researchers at UT Southwestern Medical Center have identified a gene linked to the autoimmune disease lupus, and its location on the X chromosome might help explain why females are 10 times more susceptible to the disease than males.

Released:
30-Mar-2009 12:05 AM EDT
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Article ID: 549850

Best Selling Cancer Drug Could Become First New Treatment for Lupus in 50 Years

American Autoimmune Related Diseases Association (AARDA)

A recent study of 20 people suffering from lupus nephritis, a severe kidney disorder, who were all high risk cases for kidney failure, were given the cancer drug Rituxan. Of these patients, 60 percent showed significant signs of improvement. If this study can be replicated in larger numbers, it could translate into an FDA approval of Rituxan for lupus patients. If so, it would break a 50-year record of no new drugs having been approved by the U.S. Food and Health Administration specifically for lupus.

Released:
9-Mar-2009 12:00 PM EDT
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  • Embargo expired:
    4-Mar-2009 5:00 PM EST

Article ID: 549676

Rituximab Reduces Kidney Inflammation in Patients with Lupus

American Society of Nephrology (ASN)

Treatment with the targeted drug rituximab can significantly benefit some patients with severe lupus nephritis who do not respond to conventional therapy, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The findings indicate that this immunosuppressive agent could improve the health of patients who have few other treatment options and who might otherwise develop end-stage renal disease.

Released:
3-Mar-2009 9:30 AM EST
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Article ID: 548243

Blocked Protein Prevents Lupus in Mouse Model

Jackson Laboratory

Mice from a strain that ordinarily develops systemic lupus erythematosus (SLE), but bred with a deficiency in receptor for the protein Interleukin 21, stayed healthy and exhibited none of the symptoms of the disease, researchers at The Jackson Laboratory and National Institutes of Health report.

Released:
20-Jan-2009 3:45 PM EST
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  • Embargo expired:
    29-Jul-2007 1:00 PM EDT

Article ID: 531881

Research Links Genetic Mutations to Lupus

Wake Forest Baptist Medical Center

A gene discovered by scientists at Wake Forest University School of Medicine has been linked to lupus and related autoimmune diseases. The finding, reported online in Nature Genetics, is the latest in a series of revelations that shed new light on what goes wrong in human cells to cause the diseases.

Released:
26-Jul-2007 10:35 AM EDT
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