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  • Embargo expired:
    2-Jun-2018 4:00 PM EDT

Article ID: 695393

Study of acute myeloid leukemia patients shows protein inhibitor drug safe and effective with durable remissions

University of Texas M. D. Anderson Cancer Center

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease.

Released:
31-May-2018 12:05 PM EDT
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  • Embargo expired:
    2-Jun-2018 8:00 AM EDT

Article ID: 695365

Genomic Markers Can Predict the Presence of Lynch Syndrome across a Broad Spectrum of Cancers

Memorial Sloan Kettering Cancer Center

Microsatellite instability (MSI) and DNA mismatch repair (MMR) deficiencies can predict Lynch syndrome (LS) across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center (MSK), who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology. This finding suggests that LS is linked to more types of cancer than previously thought, prompting a call for germline testing for LS in all individuals with MSI-high (MSI-H)/mismatch repair deficient (MMR-D) tumors.

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2-Jun-2018 8:00 AM EDT
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  • Embargo expired:
    2-Jun-2018 7:30 AM EDT

Article ID: 695424

Blood Test Shows Potential for Early Detection of Lung Cancer

Dana-Farber Cancer Institute

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests.

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31-May-2018 3:30 PM EDT
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  • Embargo expired:
    2-Jun-2018 7:30 AM EDT

Article ID: 695493

Long-Term IMPACT Data Find Improved Survival When Targeted Therapies Matched to Tumor-Specific Gene Mutations

University of Texas M. D. Anderson Cancer Center

Matching targeted therapies to tumor-specific gene mutations across tumor types improved progression-free survival (PFS) and overall survival (OS) in patients with advanced disease relative to those receiving non-matched treatment (NMT), according to research from The University of Texas MD Anderson Cancer Center. The researchers also found that receiving matched targeted therapy (MTT) was an independent factor for predicting longer OS.

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1-Jun-2018 4:45 PM EDT
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Article ID: 695497

Interim Results from Clinical Trial of Immunotherapy for Glioblastoma Show Significant Clinical Benefit

Roswell Park Comprehensive Cancer Center

Presenting new data at ASCO 2018, collaborators from Roswell Park Comprehensive Cancer Center, the Cleveland Clinic and MimiVax LLC report that the combination of SurVaxM plus standard therapy for patients with glioblastoma appears to be safe, effective and worthy of further evaluation.

Released:
1-Jun-2018 5:05 PM EDT
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Article ID: 695477

Sidney Kimmel Cancer Center Scientists to Present on Uveal Melanoma, Biden Cancer Initiative and More at ASCO Annual Meeting

Thomas Jefferson University

Scientists from the Sidney Kimmel Cancer Center (SKCC) at Jefferson Health will be presenting research and leading discussions on various topics, including metastatic uveal melanoma, genetic counseling in men, immunotherapy in early stage lung cancer and solid tumors, quality of life among patients receiving treatment for T cell lymphoma and updates on the Cancer Moonshot during the Biden Cancer Initiative Colloquium at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, being held June 1-5 in Chicago.

Released:
1-Jun-2018 2:40 PM EDT
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  • Embargo expired:
    1-Jun-2018 2:00 PM EDT

Article ID: 695436

Analysis: Survival Benefit for African-Americans with Advanced Prostate Cancer

Duke Health

Contrary to current perceptions, certain African-American men with advanced prostate cancer have as good a chance of survival as white men and might actually have a small advantage, according to a new analysis of more than 8,000 patients who participated in clinical trials.

Released:
1-Jun-2018 2:00 PM EDT
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  • Embargo expired:
    1-Jun-2018 2:00 PM EDT

Article ID: 695437

Black Patients Show Stronger Response to Hormone Therapy for Prostate Cancer

Duke Health

African-American men with advanced prostate cancer might be more responsive than white men to an anti-androgen drug and steroids, according to a study led by Duke Cancer Institute researchers.

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1-Jun-2018 2:00 PM EDT
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Article ID: 695459

Cleveland Clinic Cancer Center Experts Present Data at 2018 ASCO Annual Meeting

Cleveland Clinic

At the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, researchers from Cleveland Clinic Cancer Center will present data from several new studies, including a prospective clinical trial examining non-small cell lung cancer cells’ response to immunotherapy; research on germline testing for melanoma; and interim results from a study testing a vaccine for glioblastoma.

Released:
1-Jun-2018 12:05 PM EDT
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Article ID: 695362

Beyond BRCA: Examining Links between Breast Cancer, Second Primary Cancer and Inherited Genetic Mutations

Perelman School of Medicine at the University of Pennsylvania

Rates of inherited mutations in genes other than BRCA1/2 are twice as high in breast cancer patients who have had a second primary cancer – including, in some cases, different types of breast cancer – compared to patients who have only had a single breast cancer.

Released:
31-May-2018 9:55 AM EDT
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