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  • Embargo expired:
    5-Jun-2018 9:00 AM EDT

Article ID: 695598

Penn Medicine Gastrointestinal Bleeding Research Points to Need for Updated Medicare Policies

Perelman School of Medicine at the University of Pennsylvania

Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with gastrointestinal bleeding following an evaluation of patients with the condition.

Released:
5-Jun-2018 9:00 AM EDT
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  • Embargo expired:
    4-Jun-2018 11:30 AM EDT

Article ID: 695485

First Study of Neoadjuvant Use of PARP Inhibitor Shows Promise for Early-Stage, BRCA+ Breast Cancer Patients

University of Texas M. D. Anderson Cancer Center

In a small Phase II study of early-stage breast cancer patients with BRCA1/2 mutations, researchers at The University of Texas MD Anderson Cancer Center found that more than half of the women who took the PARP inhibitor talazoparib once daily prior to surgery had no evidence of disease at the time of surgery. If further validated in larger, confirmatory trials, the oral medication could replace chemotherapy for these patients.

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1-Jun-2018 3:45 PM EDT
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Article ID: 695511

More frequent screening after prostate cancer treatment not linked to improved survival

University of North Carolina Health Care System

A study by UNC Lineberger Comprehensive Cancer Center's Ronald Chen, MD, MPH, and colleagues assessed whether monitoring prostate cancer patients following treatment with a PSA test every three months versus once a year would provide a long-term survival benefit.

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4-Jun-2018 10:05 AM EDT
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  • Embargo expired:
    4-Jun-2018 9:35 AM EDT

Article ID: 695416

AI Plus Ovarian Suppression Yields Benefit in High-Risk Premenopausal Breast Cancer Patients

Dana-Farber Cancer Institute

Premenopausal women with hormone receptor-positive, HER2-negative breast cancer and a high risk of recurrence who are treated with an aromatase inhibitor plus ovarian function suppression may gain 10 to 15 percent improvement in freedom from distant recurrence at eight years, according to a new clinical trial analysis reported at the annual meeting of the American Society of Clinical Oncology.

Released:
31-May-2018 3:30 PM EDT
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  • Embargo expired:
    4-Jun-2018 9:00 AM EDT

Article ID: 695476

New Research Sparks Call for Guidelines Around High-Intensity Interval Training

Les Mills

New research has for the first time set a recommended upper limit of High-Intensity Interval Training (HIIT) at 30-40 minutes working out at above 90 percent of the maximum heart rate per week. The study findings – presented by Associate Professor Jinger Gottschall at the 2018 American College of Sports Medicine (ACSM) Annual Meeting this month – provide evidence that any more than 30-40 minutes of HIIT in a maximum training zone per week can reduce performance and potentially result in a greater risk of injury.

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1-Jun-2018 6:00 PM EDT
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Article ID: 695445

ISPOR 2018 Drew Nearly 4000 Stakeholders in Health Economics and Outcomes Research

ISPOR—The Professional Society for Health Economics and Outcomes Research

ISPOR, the professional society for health economics and outcomes research, recently concluded its ISPOR 2018 conference in Baltimore, MD, USA. The conference drew 3741 healthcare stakeholders representing 70 countries from all sectors of healthcare.

Released:
4-Jun-2018 8:05 AM EDT
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  • Embargo expired:
    3-Jun-2018 1:00 PM EDT

Article ID: 695491

Why Do Some Sleep-Deprived People Experience Worse Cognitive Functioning than Others?

Perelman School of Medicine at the University of Pennsylvania

Penn study reveals that microRNAs predict differences in cognitive impairment in memory and attention after sleep deprivation

Released:
1-Jun-2018 4:40 PM EDT
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  • Embargo expired:
    3-Jun-2018 10:00 AM EDT

Article ID: 695392

Erdafitinib Shows Promise in Urothelial Cancer Patients with Specific Mutations

University of Texas M. D. Anderson Cancer Center

In an international Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with the oral FGFR inhibitor erdafitinib (ERDA) was well-tolerated and achieved a robust response for patients with metastatic urothelial, or urinary tract, cancers harboring mutations in the FGFR3 gene.

Released:
31-May-2018 12:05 PM EDT
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  • Embargo expired:
    3-Jun-2018 7:30 AM EDT

Article ID: 695398

Landmark Study Finds More Breast Cancer Patients Can Safely Forgo Chemotherapy

Loyola University Health System

A 21-gene test could enable most patients with the most common type of early breast cancer to safely forgo chemotherapy, according to a landmark study published in the New England Journal of Medicine. Loyola Medicine oncologist Kathy Albain, MD, is among the main co-authors.

Released:
31-May-2018 1:05 PM EDT
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Article ID: 694881

Updated ALEX Trial Results Show Alectinib Further Outpacing Crizotinib in Treatment Naive ALK+ NSCLC

University of Colorado Cancer Center

Dpdated data further consolidate alectinib as the standard-of-care for first-line treatment of ALK+ non-small cell lung cancer.

Released:
3-Jun-2018 7:05 AM EDT
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