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  • Embargo expired:
    12-Jul-2018 7:00 AM EDT

Article ID: 697318

Smell Receptors in the Body Could Help Sniff Out Disease

American Physiological Society (APS)

A review of more than 200 studies reveals that olfactory receptors—proteins that bind to odors that aid the sense of smell—perform a wide range of mostly unknown functions outside the nose. The function of extra-nasal olfactory receptors has the potential to be used in the diagnosis and treatment of health conditions such as cancer.

Released:
11-Jul-2018 4:00 PM EDT
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Article ID: 697305

Researchers Clarify Role of Mutations in Glioblastoma

University of North Carolina Health Care System

Researchers investigated whether the location of the mutation within the sequence of the PIK3CA gene affected the mutation’s ability to help drive glioblastoma growth. They also tested whether mutations within certain sequences of the gene were linked to better responses to particular drugs. They found mutational status was not linked to a response to a single targeted drug, but it was to a combination of treatments.

Released:
11-Jul-2018 2:05 PM EDT
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  • Embargo expired:
    11-Jul-2018 1:00 PM EDT

Article ID: 697281

Rise of the Clones

Harvard Medical School

Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65

Released:
11-Jul-2018 10:30 AM EDT
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Article ID: 697277

Ludwig Cancer Research and Cancer Research Institute Launch Clinical Trial Combining Virotherapy and Immunotherapy to Treat Advanced Colorectal and Ovarian Cancers

Ludwig Cancer Research

Ludwig Cancer Research and the Cancer Research Institute (CRI) announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI® (durvalumab) for advanced ovarian and colorectal cancers.

Released:
11-Jul-2018 12:00 PM EDT
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Article ID: 697291

Robotic Surgery as Effective as Open Surgery for Bladder Cancer

Loyola University Health System

Robotic surgery is as effective as traditional open surgery in treating bladder cancer, according to a landmark study published in the journal Lancet.

Released:
11-Jul-2018 11:05 AM EDT
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Article ID: 697306

Ludwig Cancer Research and Cancer Research Institute Launch Clinical Trial Combining Virotherapy and Immunotherapy to Treat Advanced Colorectal and Ovarian Cancers

Cancer Research Institute and the Ludwig Cancer Research

A clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI® (durvalumab) for advanced ovarian and colorectal cancers has been initiated.

Released:
11-Jul-2018 10:00 AM EDT
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Article ID: 697263

Biochemists Discover Cause of Genome Editing Failures with Hyped CRISPR System

University of Illinois at Chicago

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.

Released:
10-Jul-2018 4:45 PM EDT
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Article ID: 697250

UC San Diego Biologists Discover Process That Neutralizes Tumors

University of California San Diego

Researchers discovered an unexpected twist in the battle versus tumors. Researchers have found that some tumor cells display not only a weapon, but also a brake, essentially becoming a neutralizing function. The unexpected mechanism could help determine whether a cancer patient will respond to immunotherapy.

Released:
10-Jul-2018 3:05 PM EDT
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Article ID: 697225

International Conference Brings Together World Leaders in Eye Cancer

Association for Research in Vision and Ophthalmology (ARVO)

The world’s leading ocular oncology scientists and clinicians are meeting this summer to discuss the latest research and treatment developments in eye cancer. The Ocular Oncogenesis and Oncology Conference (OOO) will be held by the Association for Research in Vision and Ophthalmology (ARV0) in partnership with the Champalimaud Foundation, July 18 – 21 at the Champalimaud Centre for the Unknown in Lisbon, Portugal

Released:
10-Jul-2018 2:00 PM EDT
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Article ID: 697230

Brain Metastases Common and Difficult to Treat in ROS1 Lung Cancer

University of Colorado Cancer Center

Brain metastases were found to be fairly common in stage IV ROS1-positive cancers and in 47 percent of ROS1 patients, the brain was the first and only site of progression.

Released:
10-Jul-2018 12:05 PM EDT
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