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Article ID: 699154

First Science with ALMA’s Highest-Frequency Capabilities

National Radio Astronomy Observatory

A team of scientists using the highest-frequency capabilities of the Atacama Large Millimeter/submillimeter Array (ALMA) has uncovered jets of warm water vapor streaming away from a newly forming star. The researchers also detected the “fingerprints” of an astonishing assortment of molecules near this stellar nursery.

Released:
17-Aug-2018 11:05 AM EDT
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Article ID: 699088

Empowerment Through Ideas: Teaching Effectuation in Pakistan

University of Virginia Darden School of Business

Dr. Shahid Qureshi is determined to make the world a better place through effectuation, the set of principles for entrepreneurial decision-making developed by Darden’s Professor Saras Sarasvathy, based on a rigorous study of expert entrepreneurs.

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16-Aug-2018 10:05 AM EDT
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Education

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Article ID: 699055

As Controversial EPA Rule Comment Period Comes to a Close, Data Management Expert Offers Recommendations for Implementation

Virginia Tech

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15-Aug-2018 4:05 PM EDT
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Law and Public Policy

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Article ID: 699054

UVA Darden Welcomes Eight New Professors for 2018-19 Academic Year

University of Virginia Darden School of Business

The University of Virginia Darden School of Business welcomed eight new professors to its top-ranked faculty ahead of the 2018–19 academic year. The new professors will bolster ranks in the academic areas of Quantitative Analysis, Accounting, Global Economies and Markets, and Leadership and Organizational Behavior.

Released:
15-Aug-2018 2:05 PM EDT
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Education

  • Embargo expired:
    15-Aug-2018 2:00 PM EDT

Article ID: 699038

Climate Change Sea Level Rises Could Increase Risk for More Devastating Tsunamis Worldwide

Virginia Tech

As sea levels rise due to climate change, so do the global hazards and potential devastating damages from tsunamis, according to a new study by a partnership that included Virginia Tech.

Released:
15-Aug-2018 12:25 PM EDT
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Article ID: 698814

Research Grant to Study Common Resistance to Papillary Thyroid Cancer Treatment Is Awarded to Ann-Kathrin Eisfeld, MD, by the American Thyroid Association

American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Ann-Kathrin Eisfeld, MD, Clinical Fellow in Internal Medicine at Ohio State University. The topic of Dr. Eisfeld’s project is “Novel NRAS isoform mediates BRAF-inhibitor resistance in papillary thyroid cancer—thinking outside the box to overcome ‘inevitable’ treatment failure.” Papillary thyroid cancer (PTC) is one of the 10 most common malignancies in the United States, with almost 60,000 new people diagnosed each year. While almost all patients initially respond well to the current standard treatment with radioactive iodine, almost half of them will eventually develop resistance. Therapies that can provide additional treatment options for those patients are greatly needed.

Released:
14-Aug-2018 8:05 AM EDT
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Article ID: 698721

Research Grant Focused on Identifying T3-Forming Sites in Thyroglobulin Is Awarded to Cintia Eliana Citterio, PhD, by the American Thyroid Association

American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Cintia Eliana Citterio, PhD, Assistant Professor of Genetics and Molecular Biology at the Instituto de Inmunología, Genética y Metabolismo (INIGEM), Universidad de Buenos Aires (UBA) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Dr. Citterio’s project is called “De novo triiodothyronine (T3) formation in T3 toxicosis of Graves’ Disease.” The project focuses on identifying T3-forming sites in thyroglobulin (TG, the protein from which thyroid hormone is made) that are responsible for excess T3 production in patients with autoimmune hyperthyroidism or Graves’ Disease (GD).

Released:
14-Aug-2018 8:05 AM EDT
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Article ID: 698821

Research Grant to Determine the Genes Responsible for Survival and Growth of Medullary Thyroid Cancer Is Awarded to Wayne Miles, PhD, by the American Thyroid Association

American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Wayne Miles, PhD, Assistant Professor of Molecular Genetics at the Ohio State University. Dr. Miles’s research project is entitled “Proteomic-led discovery of essential genes in Medullary Thyroid Cancer.” Medullary thyroid cancer (MTC) is caused by the malignant growth of C-cells. Although MTC represents only a small fraction (2¬4%) of all thyroid cancer cases and overall survival rates from MTC are good, patients diagnosed with advanced disease have poor five-year survival rates (28%). The genetic aberrations of the cancer result in C-cells receiving a continuous signal to grow and proliferate. To sustain their elevated growth rates, MTC cells adapt their genome (DNA), transcriptome (RNA), and proteome (the entire set of proteins expressed by a cell, tissue, or organism).

Released:
14-Aug-2018 8:00 AM EDT
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Article ID: 698826

Research Grant to Identify the Source and Mechanism of Thyroid and Kidney Comorbidity Is Awarded to Nicholas Tardi, PhD, by the American Thyroid Association

American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Nicholas J. Tardi, PhD, Instructor in Internal Medicine at Rush University Medical Center in Chicago. Dr. Tardi’s project is titled “Deiodinase 3: A Thyroid Hormone-Associated Renoprotective Protein.” The long-term goal of this project is to identify the source and mechanism of kidney and thyroid comorbidity. Thyroid hormone (TH) is a circulating, lipid-soluble molecule that plays an important physiological and developmental role in nearly all cells. Accordingly, precise control of TH activity is crucial to maintain metabolic homeostasis in several tissues.

Released:
14-Aug-2018 8:00 AM EDT
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Article ID: 698825

Research Grant to Determine How Specific Drugs Work or Fail in Anaplastic Thyroid Cancer Is Awarded to Miles Miller, PhD, by the American Thyroid Association

American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Miles Miller, PhD, principal investigator at the Massachusetts General Hospital Center for Systems Biology and Assistant Professor of Radiology at Harvard Medical School. Dr. Miller’s research project is titled “Co-opting tumor-associated macrophages in anaplastic thyroid cancer to enhance immune-checkpoint blockade response.” Treatment of advanced metastatic cancer has seen a revolution over the last several years, as new therapeutic strategies have become successful at harnessing the power of the immune system to durably attack malignant and mutated cancer cells. Immune-checkpoint blockade therapies targeting programmed-death 1 (PD1) signaling on T-cells have been successful in the treatment of solid cancers, including heavily mutated melanomas and lung cancers. Unfortunately, these treatments only work in a fraction of patients, and resistance is often associated with the presence of a type of tumor-promoting imm

Released:
13-Aug-2018 11:05 AM EDT
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