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Article ID: 697706

Scientists Reverse Aging-Associated Skin Wrinkles and Hair Loss in a Mouse Model

University of Alabama at Birmingham

When a mutation for mitochondrial dysfunction is induced in a mouse model, the mouse develops wrinkled skin and extensive hair loss in a matter of weeks. This is reversed to normal appearance when mitochondrial function is restored by turning off the gene responsible for mitochondrial dysfunction.

Released:
20-Jul-2018 10:05 AM EDT
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25-Jul-2018 5:00 PM EDT
Released to reporters:
20-Jul-2018 10:05 AM EDT

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    20-Jul-2018 5:00 AM EDT

Article ID: 697636

Drug Now in Clinical Trials for Parkinson’s Strengthens Heart Contractions in Animals

Johns Hopkins Medicine

A drug currently in clinical trials for treating symptoms of Parkinson’s disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.

Released:
19-Jul-2018 10:00 AM EDT
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23-Jul-2018 11:00 AM EDT
Released to reporters:
19-Jul-2018 4:00 PM EDT

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  • Embargo expired:
    19-Jul-2018 2:00 PM EDT

Article ID: 697455

Enzyme Identified as Possible Novel Drug Target for Sickle Cell Disease, Thalassemia

Children's Hospital of Philadelphia

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease. Tests in human cells reveal that blocking the protein reduces the characteristic sickling that distorts the shape of red blood cells and gives the disease its name.

Released:
16-Jul-2018 3:00 PM EDT
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Article ID: 697669

Memory Foam for Vascular Treatment Receives FDA Clearance

National Institute of Biomedical Imaging and Bioengineering

Shape Memory Medical recently announced FDA clearance for U.S. marketing of their IMPEDE Embolization Plug, a technology funded by NIBIB and created to block irregular blood vessels.

Released:
19-Jul-2018 1:05 PM EDT
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24-Jul-2018 11:00 AM EDT
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19-Jul-2018 12:05 PM EDT

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Article ID: 697638

GW Study Will Examine Molecular Mechanisms of Male Bias in Autism

George Washington University

With more than $2 million from the National Institute of Neurological Disorders and Stroke, a team at GW led by Chiara Manzini, PhD, will study the CC2D1A gene and its role in the development of autism in males versus females.

Released:
19-Jul-2018 9:40 AM EDT
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    19-Jul-2018 5:00 AM EDT

Article ID: 697483

‘Good Cholesterol’ May Not Always be Good for Postmenopausal Women

Health Sciences at the University of Pittsburgh

Postmenopausal factors may have an impact on the heart-protective qualities of high-density lipoproteins (HDL) – also known as ‘good cholesterol.’ The findings bring into question the current use of total HDL cholesterol to predict heart disease risk.

Released:
17-Jul-2018 10:00 AM EDT
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    18-Jul-2018 2:00 PM EDT

Article ID: 697439

Study Finds Melanoma Biomarkers Predicting Checkpoint Blocker Response

Dana-Farber Cancer Institute

Scientists at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

Released:
17-Jul-2018 9:00 AM EDT
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