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Embargo will expire:
23-May-2018 10:00 AM EDT
Released to reporters:
18-May-2018 12:05 PM EDT

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Article ID: 694802

New Mechanism Essential for Eye Lens Development Identified

University of Delaware

A team led by a University of Delaware researcher has identified the protein essential for eye lens development and clear vision. Without the protein, eyes will form cataracts; with it, lens cells are cleared and ready to see. The work is providing fundamental new knowledge on the basic underlying mechanisms involved in eye development.

Released:
18-May-2018 10:05 AM EDT
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  • Embargo expired:
    18-May-2018 9:00 AM EDT

Article ID: 694530

Cardiomyopathy Mutation Reduces Heart’s Ability to Vary Pumping Force, Study Reveals

The Rockefeller University Press

Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy disrupts the heart’s normal function. The study, which will be published May 18 in the Journal of General Physiology, reveals that the mutation prevents the heart from increasing the amount of force it produces when it needs to pump additional blood around the body.

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14-May-2018 1:05 PM EDT
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  • Embargo expired:
    17-May-2018 2:00 PM EDT

Article ID: 694664

Scientists Analyze First Ancient Human DNA From Southeast Asia

Harvard Medical School

Harvard Medical School researchers lead the first whole-genome analysis of ancient human DNA from Southeast Asia Study identifies at least three major waves of human migration into the region over the last 50,000 years, each shaping the genetics of Southeast Asia “to a remarkable extent” Findings reveal a complex interplay among archaeology, genetics and language

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16-May-2018 10:35 AM EDT
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Article ID: 694701

Improving Survival in Pancreatic Cancer with Platinum-Based Chemotherapy

Johns Hopkins Medicine

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

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17-May-2018 8:00 AM EDT
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    16-May-2018 1:00 PM EDT

Article ID: 694528

Under Certain Conditions, Bacterial Signals Set the Stage for Leukemia

University of Chicago Medical Center

A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.

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14-May-2018 1:05 PM EDT
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Article ID: 694659

Case Western Reserve University, Lucid Diagnostics Sign License Agreement to Commercialize Fast, Accurate Barrett’s Esophagus Detector

University Hospitals Cleveland Medical Center

Announcement of Case Western Reserve University and PAVmed signing a license agreement to commercialize EsoCheck technology which combines a non-invasive, cell-sampling device with highly accurate DNA biomarkers to detect Barrett's Esophagus. University Hospitals in Cleveland will implement use of the technology.

Released:
16-May-2018 9:05 AM EDT
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  • Embargo expired:
    15-May-2018 8:00 PM EDT

Article ID: 694497

Researchers Uncover New Genomic Evidence Linking Extinct Giant Ground Sloth, First Discovered by Charles Darwin, to Small Modern-Day Sloths

McMaster University

Researchers have uncovered important genomic data from the remains of an ancient giant ground sloth, or Mylodon darwinii, the emblematic creature named after Charles Darwin, whose discovery of fossilized remains in South America is considered to be one of his significant scientific achievements.

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14-May-2018 9:05 AM EDT
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Article ID: 694594

Biologists Find Mechanisms that Control Where Transcription Factors Bind

New York University

A team of biologists has determined how transcription factors, which guide gene regulation, function differently in embryonic development. The results help illuminate how cells acquire distinct functions as the embryo matures.

Released:
15-May-2018 12:05 PM EDT
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Article ID: 694607

Scientists Find Missing Factor in Gene Activation

University of California San Diego

Scientists have unraveled a mystery on how genes are activated. Genes are blocked by structures known as nucleosomes, which package DNA. How do these roadblocks clear out to allow genes to turn on? Scientists have identified a key factor that unravels nucleosomes and clears the way. They say the finding is useful in understanding diseases such as cancer.

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15-May-2018 12:05 PM EDT
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